Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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781
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781
Tocris Bioscience™ Crizotinib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 877399-52-5 Molecular Formula: C21H22Cl2FN5O
| CAS | 877399-52-5 |
|---|---|
| Molecular Formula | C21H22Cl2FN5O |
782
Tocris Bioscience™ LaKe
Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells
783
Tocris Bioscience™ SNIPER(ER)-87
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Potent and selective ERα Degrader (SNIPER)
784
Tocris Bioscience™ TC-G 1005
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Potent and selective GPBA receptor (TGR5) agonist
| CAS | 1415407-60-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | TC-G 1005 |
| Recommended Storage | Store at -20°C |
| Synonym | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone |
| Molecular Formula | C25H25N3O2 |
| Formula Weight | 399.48 |
785
Tocris Bioscience™ A 803467
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CAS: 944261-79-4 Molecular Formula: C19H16ClNO4
| CAS | 944261-79-4 |
|---|---|
| Molecular Formula | C19H16ClNO4 |
786
Tocris Bioscience™ (-)-Xestospongin C
Greener Choice
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CAS: 88903-69-9 Molecular Formula: C28H50N2O2
| CAS | 88903-69-9 |
|---|---|
| Molecular Formula | C28H50N2O2 |
787
Tocris Bioscience™ ICA 121431
Greener Choice
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CAS: 313254-51-2 Molecular Formula: C23H19N3O3S2
| CAS | 313254-51-2 |
|---|---|
| Molecular Formula | C23H19N3O3S2 |
788
Tocris Bioscience™ SMER 28
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 307538-42-7 Molecular Formula: C11H10BrN3
| CAS | 307538-42-7 |
|---|---|
| Molecular Formula | C11H10BrN3 |
789
Tocris Bioscience™ DCG IV
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent group II mGlu agonist; also NMDA agonist
| Target | Group II mGluR Agonists |
|---|---|
| CAS | 147782-19-2 |
| Solubility | Soluble to 100mM in water |
| Purity | 98% |
| Chemical Name or Material | (2 S,2 'R,3 'R)-2-(2 ',3 '-Dicarboxycyclopropyl)glycine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C7H9NO6 |
| Formula Weight | Observed MW: 203.15 |
| Assay Percent Range | >98% |
790
Tocris Bioscience™ PFI 3
Greener Choice
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Potent and selective SMARCA2/4 and polybromo 1 inhibitor
791
Tocris Bioscience™ JZL 184
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1101854-58-3 Molecular Formula: C27H24N2O9
| CAS | 1101854-58-3 |
|---|---|
| Molecular Formula | C27H24N2O9 |
792
Tocris Bioscience™ GX 201
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective Nav1.7 blocker; analgesic
793
Tocris Bioscience™ TC-G 1008
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective GPR39 agonist
| CAS | 1621175-65-2 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | TC-G 1008 |
| Recommended Storage | Store at 4°C |
| Synonym | N-[3-Chloro-4-[[[2-(methylamino)-6-(2-pyridinyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonate |
| Molecular Formula | C18H19ClN6O2S |
| Formula Weight | 418.9 |
794
Tocris Bioscience™ Thalidomide 4'-ether-alkylC6-amine
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Thalidomide-alkylC6-amine
795
Tocris Bioscience™ GSK 3787
Greener Choice
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CAS: 188591-46-0 Molecular Formula: C15H12ClF3N2O3S
| CAS | 188591-46-0 |
|---|---|
| Molecular Formula | C15H12ClF3N2O3S |